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Efficient in planta production of amidated antimicrobial peptides that are active against drug-resistant ESKAPE pathogens

Antimicrobial peptides (AMPs) are promising next-generation antibiotics that can be used to combat drug-resistant pathogens. However, the high cost involved in AMP synthesis and their short plasma half-life render their clinical translation a challenge. To address these shortcomings, we report effic...

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Detalles Bibliográficos
Autores principales: Chaudhary, Shahid, Ali, Zahir, Tehseen, Muhammad, Haney, Evan F., Pantoja-Angles, Aarón, Alshehri, Salwa, Wang, Tiannyu, Clancy, Gerard J., Ayach, Maya, Hauser, Charlotte, Hong, Pei-Ying, Hamdan, Samir M., Hancock, Robert E. W., Mahfouz, Magdy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020429/
https://www.ncbi.nlm.nih.gov/pubmed/36928189
http://dx.doi.org/10.1038/s41467-023-37003-z