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Mechanism underlying delayed rectifying in human voltage-mediated activation Eag2 channel
The transmembrane voltage gradient is a general physico-chemical cue that regulates diverse biological function through voltage-gated ion channels. How voltage sensing mediates ion flows remains unknown at the molecular level. Here, we report six conformations of the human Eag2 (hEag2) ranging from...
Autores principales: | Zhang, Mingfeng, Shan, Yuanyue, Pei, Duanqing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020445/ https://www.ncbi.nlm.nih.gov/pubmed/36928654 http://dx.doi.org/10.1038/s41467-023-37204-6 |
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