Dexmedetomidine improves acute lung injury by activating autophagy in a rat hemorrhagic shock and resuscitation model

Dexmedetomidine (DEX) can reduce lung injury in a hemorrhagic shock (HS) resuscitation (HSR) model in rats by inhibiting inflammation. Here, we aimed to investigate if these effects of DEX are due to autophagy activation. Therefore, we established HSR rat models and divided them into four groups. HS...

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Detalles Bibliográficos
Autores principales: Lu, Yifu, Shimizu, Hiroko, Nakamura, Ryu, Li, Yaqiang, Sakamoto, Risa, Omori, Emiko, Takahashi, Toru, Morimatsu, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020563/
https://www.ncbi.nlm.nih.gov/pubmed/36927753
http://dx.doi.org/10.1038/s41598-023-31483-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020563/
https://www.ncbi.nlm.nih.gov/pubmed/36927753
http://dx.doi.org/10.1038/s41598-023-31483-1

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