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In silico analysis to identify miR-1271-5p/PLCB4 (phospholipase C Beta 4) axis mediated oxaliplatin resistance in metastatic colorectal cancer

Oxaliplatin (OXA) is the first-line chemotherapy drug for metastatic colorectal cancer (mCRC), and the emergence of drug resistance is a major clinical challenge. Although there have been numerous studies on OXA resistance, but its underlying molecular mechanisms are still unclear. This study aims t...

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Detalles Bibliográficos
Autores principales: Lee, Cheng-Chin, Lee, Ai-Wei, Wei, Po-Li, Liu, Yi-Shin, Chang, Yu-Jia, Huang, Chien-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020571/
https://www.ncbi.nlm.nih.gov/pubmed/36927770
http://dx.doi.org/10.1038/s41598-023-31331-2