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In silico analysis to identify miR-1271-5p/PLCB4 (phospholipase C Beta 4) axis mediated oxaliplatin resistance in metastatic colorectal cancer
Oxaliplatin (OXA) is the first-line chemotherapy drug for metastatic colorectal cancer (mCRC), and the emergence of drug resistance is a major clinical challenge. Although there have been numerous studies on OXA resistance, but its underlying molecular mechanisms are still unclear. This study aims t...
Autores principales: | Lee, Cheng-Chin, Lee, Ai-Wei, Wei, Po-Li, Liu, Yi-Shin, Chang, Yu-Jia, Huang, Chien-Yu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020571/ https://www.ncbi.nlm.nih.gov/pubmed/36927770 http://dx.doi.org/10.1038/s41598-023-31331-2 |
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