Characterization of a novel potency endpoint for the evaluation of immune checkpoint blockade in humanized mice

INTRODUCTION: Humanized mice are emerging as valuable models to experimentally evaluate the impact of different immunotherapeutics on the human immune system. These immunodeficient mice are engrafted with human cells or tissues, that then mimic the human immune system, offering an alternative and po...

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Detalles Bibliográficos
Autores principales: Matas-Céspedes, Alba, Lapointe, Jean-Martin, Elder, Matthew J., Browne, Gareth J., Dovedi, Simon J., de Haan, Lolke, Maguire, Shaun, Stebbings, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020612/
https://www.ncbi.nlm.nih.gov/pubmed/36936963
http://dx.doi.org/10.3389/fimmu.2023.1107848

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020612/
https://www.ncbi.nlm.nih.gov/pubmed/36936963
http://dx.doi.org/10.3389/fimmu.2023.1107848

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