Oxidation modulates LINGO2-induced inactivation of large conductance, Ca(2+)-activated potassium channels

Ca(2+) and voltage-activated K(+) (BK) channels are ubiquitous ion channels that can be modulated by accessory proteins, including β, γ, and LINGO1 BK subunits. In this study, we utilized a combination of site-directed mutagenesis, patch clamp electrophysiology, and molecular modeling to investigate...

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Detalles Bibliográficos
Autores principales: Dudem, Srikanth, Boon, Pei Xin, Mullins, Nicholas, McClafferty, Heather, Shipston, Michael J., Wilkinson, Richard D.A., Lobb, Ian, Sergeant, Gerard P., Thornbury, Keith D., Tikhonova, Irina G., Hollywood, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020666/
https://www.ncbi.nlm.nih.gov/pubmed/36738787
http://dx.doi.org/10.1016/j.jbc.2023.102975

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020666/
https://www.ncbi.nlm.nih.gov/pubmed/36738787
http://dx.doi.org/10.1016/j.jbc.2023.102975

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