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Integration of molecular modelling and in vitro studies to inhibit LexA proteolysis
INTRODUCTION: As antibiotic resistance has become more prevalent, the social and economic impacts are increasingly pressing. Indeed, bacteria have developed the SOS response which facilitates the evolution of resistance under genotoxic stress. The transcriptional repressor, LexA, plays a key role in...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020695/ https://www.ncbi.nlm.nih.gov/pubmed/36936756 http://dx.doi.org/10.3389/fcimb.2023.1051602 |