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Inhibition of LXR controls the polarization of human inflammatory macrophages through upregulation of MAFB

Monocyte-derived macrophages contribute to pathogenesis in inflammatory diseases and their effector functions greatly depend on the prevailing extracellular milieu. Whereas M-CSF primes macrophages for acquisition of an anti-inflammatory profile, GM-CSF drives the generation of T cell-stimulatory an...

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Detalles Bibliográficos
Autores principales: de la Aleja, Arturo González, Herrero, Cristina, Torres-Torresano, Mónica, Schiaffino, María Teresa, del Castillo, Alejandro, Alonso, Bárbara, Vega, Miguel A., Puig-Kröger, Amaya, Castrillo, Antonio, Corbí, Ángel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020776/
https://www.ncbi.nlm.nih.gov/pubmed/36930354
http://dx.doi.org/10.1007/s00018-023-04745-4