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The Role of TRiC-enhanced Actin Folding in Leber Congenital Amaurosis

PURPOSE: Mutations in TCP-1 ring complex (TRiC) have been associated with Leber Congenital Amaurosis (LCA). TRiC is involved in protein folding and has 8 essential subunits including CCT5. Herein, we studied the retina of TRiC mutant zebrafish to evaluate the possible role of impaired actin and tubu...

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Detalles Bibliográficos
Autores principales: Berger, Silke, D. Currie, Peter, Berger, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PUBLISHED BY KNOWLEDGE E 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020782/
https://www.ncbi.nlm.nih.gov/pubmed/36937198
http://dx.doi.org/10.18502/jovr.v18i1.12726