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The Antitumor Effect of Topotecan Loaded Thiolated Chitosan-Dextran Nanoparticles for Intravitreal Chemotherapy: A Xenograft Retinoblastoma Model

PURPOSE: This research intended to fabricate the thiolated chitosan-dextran nanoparticles (NPs) containing topotecan (TPH-CMD-TCS-NPs) to assess the ability of NPs in improving the efficacy of intravitreal chemotherapy of retinoblastoma in a rabbit xenograft model. METHODS: The coacervation process...

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Detalles Bibliográficos
Autores principales: Delrish, Elham, Jabbarvand, Mahmoud, Ghassemi, Fariba, Asadi Amoli, Fahimeh, Atyabi, Fatemeh, Heidari Keshel, Saeed, Lashay, Alireza, Sadat Mirzazadeh Tekie, Farnaz, Soleimani, Masoud, Dinarvand, Rassoul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PUBLISHED BY KNOWLEDGE E 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020795/
https://www.ncbi.nlm.nih.gov/pubmed/36937194
http://dx.doi.org/10.18502/jovr.v18i1.12727