Select HDAC Inhibitors Enhance Osteolysis and Bone Metastasis Outgrowth but Can Be Mitigated With Bisphosphonate Therapy

Breast cancer has a high predilection for spreading to bone with approximately 70% of patients who succumb to disease harboring bone disseminated tumor cells. Despite this high prevalence, treatments for bone metastatic breast cancer predominantly manage morbidities, including pain and hypercalcemia...

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Detalles Bibliográficos
Autores principales: Clements, Miranda E, Holtslander, Lauren, Johnson, Joshua R, Johnson, Rachelle W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020917/
https://www.ncbi.nlm.nih.gov/pubmed/36936362
http://dx.doi.org/10.1002/jbm4.10694

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020917/
https://www.ncbi.nlm.nih.gov/pubmed/36936362
http://dx.doi.org/10.1002/jbm4.10694

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