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Structural basis for antibody recognition of vulnerable epitopes on Nipah virus F protein

Nipah virus (NiV) is a pathogenic paramyxovirus that causes fatal encephalitis in humans. Two envelope glycoproteins, the attachment protein (G/RBP) and fusion protein (F), facilitate entry into host cells. Due to its vital role, NiV F presents an attractive target for developing vaccines and therap...

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Detalles Bibliográficos
Autores principales: Byrne, Patrick O., Fisher, Brian E., Ambrozak, David R., Blade, Elizabeth G., Tsybovsky, Yaroslav, Graham, Barney S., McLellan, Jason S., Loomis, Rebecca J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10021056/
https://www.ncbi.nlm.nih.gov/pubmed/36932063
http://dx.doi.org/10.1038/s41467-023-36995-y