Exosomes secreted from bone marrow mesenchymal stem cells suppress cardiomyocyte hypertrophy through Hippo-YAP pathway in heart failure

Mesenchymal stem cells-derived exosomes (MSCs-exosomes) reportedly possess cardioprotective effects. This study investigated the therapeutic potential and mechanisms of MSCs-exosomes on heart failure (HF). H9c2 cells were used to establish a cardiomyocyte hypertrophy model by angiotensin II (Ang II)...

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Detalles Bibliográficos
Autores principales: Ren, Yu, Wu, Yun, He, Wenshuai, Tian, Yingjie, Zhao, Xingsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Genética 2023
Materias:
Human and Medical Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10021068/
https://www.ncbi.nlm.nih.gov/pubmed/36929834
http://dx.doi.org/10.1590/1678-4685-GMB-2022-0221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10021068/
https://www.ncbi.nlm.nih.gov/pubmed/36929834
http://dx.doi.org/10.1590/1678-4685-GMB-2022-0221

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