Cargando…

Definitions matter: Heterogeneity of COVID-19 disease severity criteria and incomplete reporting compromise meta-analysis

Therapeutic efficacy in COVID-19 is dependent upon disease severity (treatment effect heterogeneity). Unfortunately, definitions of severity vary widely. This compromises the meta-analysis of randomised controlled trials (RCTs) and the therapeutic guidelines derived from them. The World Health Organ...

Descripción completa

Detalles Bibliográficos
Autores principales: Guérin, Philippe J., McLean, Alistair R. D., Rashan, Sumayyah, Lawal, AbdulAzeez, Watson, James A., Strub-Wourgaft, Nathalie, White, Nicholas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10021556/
https://www.ncbi.nlm.nih.gov/pubmed/36962738
http://dx.doi.org/10.1371/journal.pgph.0000561