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Single-cell transcriptome reveals Staphylococcus aureus modulating fibroblast differentiation in the bone-implant interface

BACKGROUND: This study aimed to delineate the cell heterogeneity in the bone-implant interface and investigate the fibroblast responses to implant-associated S. aureus infection. METHODS: Single-cell RNA sequencing of human periprosthetic tissues from patients with periprosthetic joint infection (PJ...

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Detalles Bibliográficos
Autores principales: Yu, Jinlong, Wang, Boyong, Zhang, Feiyang, Ren, Zun, Jiang, Feng, Hamushan, Musha, Li, Mingzhang, Guo, Geyong, Shen, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10021980/
https://www.ncbi.nlm.nih.gov/pubmed/36927352
http://dx.doi.org/10.1186/s10020-023-00632-7