Cargando…

Single-cell transcriptome reveals Staphylococcus aureus modulating fibroblast differentiation in the bone-implant interface

BACKGROUND: This study aimed to delineate the cell heterogeneity in the bone-implant interface and investigate the fibroblast responses to implant-associated S. aureus infection. METHODS: Single-cell RNA sequencing of human periprosthetic tissues from patients with periprosthetic joint infection (PJ...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, Jinlong, Wang, Boyong, Zhang, Feiyang, Ren, Zun, Jiang, Feng, Hamushan, Musha, Li, Mingzhang, Guo, Geyong, Shen, Hao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10021980/ https://www.ncbi.nlm.nih.gov/pubmed/36927352 http://dx.doi.org/10.1186/s10020-023-00632-7

Ejemplares similares

Identification of Staphylococcus aureus virulence-modulating RNA from transcriptomics data with machine learning
por: Yu, Jinlong, et al.
Publicado: (2023)

A General Map of Transcriptional Expression of Virulence, Metabolism, and Biofilm Formation Adaptive Changes of Staphylococcus aureus When Exposed to Different Antimicrobials
por: Ren, Zun, et al.
Publicado: (2022)

Repurposed Fenoprofen Targeting SaeR Attenuates Staphylococcus aureus Virulence in Implant-Associated Infections
por: Jiang, Feng, et al.
Publicado: (2023)

Trends in microbiological epidemiology of orthopedic infections: a large retrospective study from 2008 to 2021
por: Wang, Boyong, et al.
Publicado: (2023)

Interactions between Macrophages and Biofilm during Staphylococcus aureus-Associated Implant Infection: Difficulties and Solutions
por: Li, Mingzhang, et al.
Publicado: (2023)

Thermonucleases Contribute to Staphylococcus aureus Biofilm Formation in Implant-Associated Infections–A Redundant and Complementary Story
por: Yu, Jinlong, et al.
Publicado: (2021)

Key role of quorum‐sensing mutations in the development of Staphylococcus aureus clinical device‐associated infection
por: He, Lei, et al.
Publicado: (2022)

High-purity magnesium screws modulate macrophage polarization during the tendon–bone healing process in the anterior cruciate ligament reconstruction rabbit model
por: Cheng, PengFei, et al.
Publicado: (2022)

High-purity magnesium pin enhances bone consolidation in distraction osteogenesis via regulating Ptch protein activating Hedgehog-alternative Wnt signaling
por: Hamushan, Musha, et al.
Publicado: (2020)

Chiral Supramolecular Hydrogel Loaded with Dimethyloxalyglycine to Accelerate Chronic Diabetic Wound Healing by Promoting Cell Proliferation and Angiogenesis
por: Zhang, Yubo, et al.
Publicado: (2022)

Antimicrobial characteristics of Berberine against prosthetic joint infection-related Staphylococcus aureus of different multi-locus sequence types
por: Tan, Jiaqi, et al.
Publicado: (2019)

Implant bone interface /
Publicado: (1990)

Virtual Screening for Novel SarA Inhibitors to Prevent Biofilm Formation of Staphylococcus aureus in Prosthetic Joint Infections
por: Yu, Jinlong, et al.
Publicado: (2020)

The Synergistic Effect of Nicotine and Staphylococcus aureus on Peri-Implant Infections
por: Hu, Yao, et al.
Publicado: (2021)

Staphylococcus aureus Cell Wall Biosynthesis Modulates Bone Invasion and Osteomyelitis Pathogenesis
por: Masters, Elysia A., et al.
Publicado: (2021)

Modulation of Staphylococcus aureus spreading by water
por: Lin, Mei-Hui, et al.
Publicado: (2016)

A Bone-Targeting Enoxacin Delivery System to Eradicate Staphylococcus Aureus-Related Implantation Infections and Bone Loss
por: Yao, Cong, et al.
Publicado: (2021)

Isolation and characterization of the Staphylococcus aureus bacteriophage vB_SauS_SA2
por: Wang, Jia, et al.
Publicado: (2019)

Engineering the Bone-Implant Interface
por: Mangano, Francesco, et al.
Publicado: (2018)

Elastography of the bone-implant interface
por: Hériveaux, Yoann, et al.
Publicado: (2019)

Exploring the transcriptome of Staphylococcus aureus in its natural niche
por: Chaves-Moreno, Diego, et al.
Publicado: (2016)

Transcriptome change of Staphylococcus aureus in infected mouse liver
por: Hamamoto, Hiroshi, et al.
Publicado: (2022)

The effects of Staphylococcus aureus biofilm conditioned media on 3T3 fibroblasts
por: Madden, Leigh, et al.
Publicado: (2021)

Potassium Uptake Modulates Staphylococcus aureus Metabolism
por: Gries, Casey M., et al.
Publicado: (2016)

Prevalence of Staphylococcus aureus, Methicillin-Resistant Staphylococcus aureus and Potential Risk Factors in Selected Dairy Farms at the Interface of Animal and Human in Bishoftu, Ethiopia
por: Tibebu, Lakech, et al.
Publicado: (2021)

Rabbit model of Staphylococcus aureus implant-associated spinal infection
por: Gordon, Oren, et al.
Publicado: (2020)

Transcriptome Analysis of Responses to Rhodomyrtone in Methicillin-Resistant Staphylococcus aureus
por: Sianglum, Wipawadee, et al.
Publicado: (2012)

Changes in the Staphylococcus aureus Transcriptome during Early Adaptation to the Lung
por: Chaffin, Donald O., et al.
Publicado: (2012)

Transcriptome analysis of the biofilm formed by methicillin-susceptible Staphylococcus aureus
por: Tan, Xiaojuan, et al.
Publicado: (2015)

The Staphylococcus aureus Transcriptome during Cystic Fibrosis Lung Infection
por: Ibberson, Carolyn B., et al.
Publicado: (2019)

Global Transcriptomic Response of Staphylococcus aureus to Virulent Bacteriophage Infection
por: Kuptsov, Nikita, et al.
Publicado: (2022)

3D Cocultures of Osteoblasts and Staphylococcus aureus on Biomimetic Bone Scaffolds as a Tool to Investigate the Host–Pathogen Interface in Osteomyelitis
por: Parente, Raffaella, et al.
Publicado: (2021)

Staphylococcus aureus and Staphylococcus epidermidis Virulence Strains as Causative Agents of Persistent Infections in Breast Implants
por: Chessa, Daniela, et al.
Publicado: (2016)

Modulation of Drug Resistance in Staphylococcus aureus with Coumarin Derivatives
por: de Araújo, Rodrigo Santos Aquino, et al.
Publicado: (2016)

Environmental factors modulate biofilm formation by Staphylococcus aureus
por: Liu, Ying, et al.
Publicado: (2020)

Osseointegration of zirconia implants: an SEM observation of the bone-implant interface
por: Depprich, Rita, et al.
Publicado: (2008)

Revealing fosfomycin primary effect on Staphylococcus aureus transcriptome: modulation of cell envelope biosynthesis and phosphoenolpyruvate induced starvation
por: Petek, Marko, et al.
Publicado: (2010)

Diabetic Mouse Model of Orthopaedic Implant-Related Staphylococcus Aureus Infection
por: Lovati, Arianna B., et al.
Publicado: (2013)

Cost-effectiveness of Preoperative Staphylococcus aureus Screening and Decolonization in Cochlear Implantation
por: Kirchner, Gregory J., et al.
Publicado: (2019)

IL-1β Promotes Staphylococcus aureus Biofilms on Implants in vivo
por: Gutierrez Jauregui, Rodrigo, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_tb9tela2qmvkp6lcbndds7pt1p