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Maternal hyperglycemia inhibits pulmonary vasculogenesis during mouse fetal lung development by promoting GβL Ubiquitination-dependent mammalian target of Rapamycin assembly

BACKGROUND: Gestational diabetes mellitus (GDM) is associated with retarded lung development and poor lung health in offspring. Mammalian target of rapamycin (mTOR) is a key regulator of vasculogenesis and angiogenesis. The aim of this study was to investigate the role mTOR plays in pulmonary vascul...

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Detalles Bibliográficos
Autores principales: Luo, Qingqing, Chai, Xinqun, Xin, Xiaoyan, Ouyang, Weixiang, Deng, Feitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10021989/
https://www.ncbi.nlm.nih.gov/pubmed/36927703
http://dx.doi.org/10.1186/s13098-022-00974-y