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Maternal hyperglycemia inhibits pulmonary vasculogenesis during mouse fetal lung development by promoting GβL Ubiquitination-dependent mammalian target of Rapamycin assembly
BACKGROUND: Gestational diabetes mellitus (GDM) is associated with retarded lung development and poor lung health in offspring. Mammalian target of rapamycin (mTOR) is a key regulator of vasculogenesis and angiogenesis. The aim of this study was to investigate the role mTOR plays in pulmonary vascul...
Autores principales: | Luo, Qingqing, Chai, Xinqun, Xin, Xiaoyan, Ouyang, Weixiang, Deng, Feitao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10021989/ https://www.ncbi.nlm.nih.gov/pubmed/36927703 http://dx.doi.org/10.1186/s13098-022-00974-y |
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