An integrated approach of network pharmacology, molecular docking, and experimental verification uncovers kaempferol as the effective modulator of HSD17B1 for treatment of endometrial cancer

BACKGROUND: Endometrial cancer (EC) is one of the most common gynecological malignancies globally, and the development of innovative, effective drugs against EC remains a key issue. Phytoestrogen kaempferol exhibits anti-cancer effects, but the action mechanisms are still unclear. METHOD: MTT assays...

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Detalles Bibliográficos
Autores principales: Ruan, Guan-Yu, Ye, Li-Xiang, Lin, Jian-Song, Lin, Hong-Yu, Yu, Li-Rui, Wang, Cheng-Yan, Mao, Xiao-Dan, Zhang, Shui-Hua, Sun, Peng-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10022092/
https://www.ncbi.nlm.nih.gov/pubmed/36932403
http://dx.doi.org/10.1186/s12967-023-04048-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10022092/
https://www.ncbi.nlm.nih.gov/pubmed/36932403
http://dx.doi.org/10.1186/s12967-023-04048-z

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