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METTL3 promotes chemoresistance in small cell lung cancer by inducing mitophagy

BACKGROUND: Small cell lung cancer (SCLC) is the most aggressive subtype of lung cancer. Although most patients are initially sensitive to first-line combination chemotherapy with cisplatin and etoposide, chemotherapy drug resistance easily develops and quickly leads to tumour progression. Therefore...

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Detalles Bibliográficos
Autores principales: Sun, Yueqin, Shen, Weitao, Hu, Shulu, Lyu, Qiong, Wang, Qiongyao, Wei, Ting, Zhu, Weiliang, Zhang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10022264/
https://www.ncbi.nlm.nih.gov/pubmed/36932427
http://dx.doi.org/10.1186/s13046-023-02638-9