Favoring the hierarchical constraint in penalized survival models for randomized trials in precision medicine

BACKGROUND: The research of biomarker-treatment interactions is commonly investigated in randomized clinical trials (RCT) for improving medicine precision. The hierarchical interaction constraint states that an interaction should only be in a model if its main effects are also in the model. However,...

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Detalles Bibliográficos
Autores principales: Belhechmi, Shaima, Le Teuff, Gwénaël, De Bin, Riccardo, Rotolo, Federico, Michiels, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10022294/
https://www.ncbi.nlm.nih.gov/pubmed/36927444
http://dx.doi.org/10.1186/s12859-023-05162-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10022294/
https://www.ncbi.nlm.nih.gov/pubmed/36927444
http://dx.doi.org/10.1186/s12859-023-05162-x

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