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In vitro and in silico evaluations of actinomycin X(2)and actinomycin D as potent anti-tuberculosis agents

BACKGROUND: Multidrug-resistant tuberculosis (MDR-TB) is one of the world’s most devastating contagious diseases and is caused by the MDR-Mycobacterium tuberculosis (MDR-Mtb) bacteria. It is therefore essential to identify novel anti-TB drug candidates and target proteins to treat MDR-TB. Here, in v...

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Detalles Bibliográficos
Autores principales: Qureshi, Kamal Ahmad, Azam, Faizul, Fatmi, Muhammad Qaiser, Imtiaz, Mahrukh, Prajapati, Dinesh Kumar, Rai, Pankaj Kumar, Jaremko, Mariusz, Emwas, Abdul-Hamid, Elhassan, Gamal Osman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10022501/
https://www.ncbi.nlm.nih.gov/pubmed/36935926
http://dx.doi.org/10.7717/peerj.14502