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In vitro and in silico evaluations of actinomycin X(2)and actinomycin D as potent anti-tuberculosis agents
BACKGROUND: Multidrug-resistant tuberculosis (MDR-TB) is one of the world’s most devastating contagious diseases and is caused by the MDR-Mycobacterium tuberculosis (MDR-Mtb) bacteria. It is therefore essential to identify novel anti-TB drug candidates and target proteins to treat MDR-TB. Here, in v...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10022501/ https://www.ncbi.nlm.nih.gov/pubmed/36935926 http://dx.doi.org/10.7717/peerj.14502 |