Lamin A/C phosphorylation at serine 22 is a conserved heat shock response to regulate nuclear adaptation during stress

The heat shock (HS) response is crucial for cell survival in harmful environments. Nuclear lamin A/C, encoded by the LMNA gene, contributes towards altered gene expression during HS, but the underlying mechanisms are poorly understood. Here, we show that upon HS, lamin A/C was reversibly phosphoryla...

Descripción completa

Detalles Bibliográficos
Autores principales: Virtanen, Laura, Holm, Emilia, Halme, Mona, West, Gun, Lindholm, Fanny, Gullmets, Josef, Irjala, Juho, Heliö, Tiina, Padzik, Artur, Meinander, Annika, Eriksson, John E., Taimen, Pekka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10022683/
https://www.ncbi.nlm.nih.gov/pubmed/36695453
http://dx.doi.org/10.1242/jcs.259788

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10022683/
https://www.ncbi.nlm.nih.gov/pubmed/36695453
http://dx.doi.org/10.1242/jcs.259788

Ejemplares similares