Distinct role of ERp57 and ERdj5 as a disulfide isomerase and reductase during ER protein folding

Proteins entering the secretory pathway need to attain native disulfide pairings to fold correctly. For proteins with complex disulfides, this process requires the reduction and isomerisation of non-native disulfides. Two key members of the protein disulfide isomerase (PDI) family, ERp57 and ERdj5 (...

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Detalles Bibliográficos
Autores principales: Robinson, Philip John, Pringle, Marie Anne, Fleming, Bethany, Bulleid, Neil John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10022741/
https://www.ncbi.nlm.nih.gov/pubmed/36655611
http://dx.doi.org/10.1242/jcs.260656

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10022741/
https://www.ncbi.nlm.nih.gov/pubmed/36655611
http://dx.doi.org/10.1242/jcs.260656

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