LRRK1 functions as a scaffold for PTP1B-mediated EGFR sorting into ILVs at the ER–endosome contact site

Proper control of epidermal growth factor receptor (EGFR) signaling is important for maintaining cellular homeostasis. Given that EGFR signaling occurs at the plasma membrane and endosomes following internalization, endosomal trafficking of EGFR spatiotemporally regulates EGFR signaling. In this pro...

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Detalles Bibliográficos
Autores principales: Hanafusa, Hiroshi, Fujita, Keitaro, Kamio, Misa, Iida, Shiori, Tamura, Yasushi, Hisamoto, Naoki, Matsumoto, Kunihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10022742/
https://www.ncbi.nlm.nih.gov/pubmed/36744428
http://dx.doi.org/10.1242/jcs.260566

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10022742/
https://www.ncbi.nlm.nih.gov/pubmed/36744428
http://dx.doi.org/10.1242/jcs.260566

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