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Intravital imaging of Wnt/β-catenin and ATF2-dependent signalling pathways during tumour cell invasion and metastasis

Wnt signalling has been implicated as a driver of tumour cell metastasis, but less is known about which branches of Wnt signalling are involved and when they act in the metastatic cascade. Here, using a unique intravital imaging platform and fluorescent reporters, we visualised β-catenin/TCF-depende...

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Detalles Bibliográficos
Autores principales: Stoletov, Konstantin, Sanchez, Saray, Gorroño, Irantzu, Rabano, Miriam, Vivanco, Maria d. M., Kypta, Robert, Lewis, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10022745/
https://www.ncbi.nlm.nih.gov/pubmed/36621522
http://dx.doi.org/10.1242/jcs.260285