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Physics-based generative model of curvature sensing peptides; distinguishing sensors from binders
Proteins can specifically bind to curved membranes through curvature-induced hydrophobic lipid packing defects. The chemical diversity among such curvature “sensors” challenges our understanding of how they differ from general membrane “binders” that bind without curvature selectivity. Here, we comb...
Autores principales: | van Hilten, Niek, Methorst, Jeroen, Verwei, Nino, Risselada, Herre Jelger |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10022891/ https://www.ncbi.nlm.nih.gov/pubmed/36930719 http://dx.doi.org/10.1126/sciadv.ade8839 |
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