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Plant and prokaryotic TIR domains generate distinct cyclic ADPR NADase products

Toll/interleukin-1 receptor (TIR) domain proteins function in cell death and immunity. In plants and bacteria, TIR domains are often enzymes that produce isomers of cyclic adenosine 5′-diphosphate–ribose (cADPR) as putative immune signaling molecules. The identity and functional conservation of cADP...

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Detalles Bibliográficos
Autores principales: Bayless, Adam M., Chen, Sisi, Ogden, Sam C., Xu, Xiaoyan, Sidda, John D., Manik, Mohammad K., Li, Sulin, Kobe, Bostjan, Ve, Thomas, Song, Lijiang, Grant, Murray, Wan, Li, Nishimura, Marc T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10022894/
https://www.ncbi.nlm.nih.gov/pubmed/36930706
http://dx.doi.org/10.1126/sciadv.ade8487