Structural insights into the assembly of gp130 family cytokine signaling complexes

The interleukin-6 (IL-6) family cytokines signal through gp130 receptor homodimerization or heterodimerization with a second signaling receptor and play crucial roles in various cellular processes. We determined cryo–electron microscopy structures of five signaling complexes of this family, containi...

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Detalles Bibliográficos
Autores principales: Zhou, Yi, Stevis, Panayiotis E., Cao, Jing, Saotome, Kei, Wu, Jiaxi, Glatman Zaretsky, Arielle, Haxhinasto, Sokol, Yancopoulos, George D., Murphy, Andrew J., Sleeman, Mark W., Olson, William C., Franklin, Matthew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10022904/
https://www.ncbi.nlm.nih.gov/pubmed/36930708
http://dx.doi.org/10.1126/sciadv.ade4395

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10022904/
https://www.ncbi.nlm.nih.gov/pubmed/36930708
http://dx.doi.org/10.1126/sciadv.ade4395

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