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Structural insights into the assembly of gp130 family cytokine signaling complexes

The interleukin-6 (IL-6) family cytokines signal through gp130 receptor homodimerization or heterodimerization with a second signaling receptor and play crucial roles in various cellular processes. We determined cryo–electron microscopy structures of five signaling complexes of this family, containi...

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Detalles Bibliográficos
Autores principales:	Zhou, Yi, Stevis, Panayiotis E., Cao, Jing, Saotome, Kei, Wu, Jiaxi, Glatman Zaretsky, Arielle, Haxhinasto, Sokol, Yancopoulos, George D., Murphy, Andrew J., Sleeman, Mark W., Olson, William C., Franklin, Matthew C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2023
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10022904/ https://www.ncbi.nlm.nih.gov/pubmed/36930708 http://dx.doi.org/10.1126/sciadv.ade4395

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