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Large vesicle extrusions from C. elegans neurons are consumed and stimulated by glial-like phagocytosis activity of the neighboring cell

Caenorhabditis elegans neurons under stress can produce giant vesicles, several microns in diameter, called exophers. Current models suggest that exophers are neuroprotective, providing a mechanism for stressed neurons to eject toxic protein aggregates and organelles. However, little is known of the...

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Detalles Bibliográficos
Autores principales: Wang, Yu, Arnold, Meghan Lee, Smart, Anna Joelle, Wang, Guoqiang, Androwski, Rebecca J, Morera, Andres, Nguyen, Ken CQ, Schweinsberg, Peter J, Bai, Ge, Cooper, Jason, Hall, David H, Driscoll, Monica, Grant, Barth D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10023159/
https://www.ncbi.nlm.nih.gov/pubmed/36861960
http://dx.doi.org/10.7554/eLife.82227