An update on the current status and prospects of nitrosation pathways and possible root causes of nitrosamine formation in various pharmaceuticals

Over the last two years, global regulatory authorities have raised safety concerns on nitrosamine contamination in several drug classes, including angiotensin II receptor antagonists, histamine-2 receptor antagonists, antimicrobial agents, and antidiabetic drugs. To avoid carcinogenic and mutagenic...

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Detalles Bibliográficos
Autores principales: Wichitnithad, Wisut, Nantaphol, Siriwan, Noppakhunsomboon, Kachathong, Rojsitthisak, Pornchai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10023554/
https://www.ncbi.nlm.nih.gov/pubmed/36942272
http://dx.doi.org/10.1016/j.jsps.2022.12.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10023554/
https://www.ncbi.nlm.nih.gov/pubmed/36942272
http://dx.doi.org/10.1016/j.jsps.2022.12.010

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