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An update on the current status and prospects of nitrosation pathways and possible root causes of nitrosamine formation in various pharmaceuticals
Over the last two years, global regulatory authorities have raised safety concerns on nitrosamine contamination in several drug classes, including angiotensin II receptor antagonists, histamine-2 receptor antagonists, antimicrobial agents, and antidiabetic drugs. To avoid carcinogenic and mutagenic...
Autores principales: | Wichitnithad, Wisut, Nantaphol, Siriwan, Noppakhunsomboon, Kachathong, Rojsitthisak, Pornchai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10023554/ https://www.ncbi.nlm.nih.gov/pubmed/36942272 http://dx.doi.org/10.1016/j.jsps.2022.12.010 |
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