EGOC inhibits TOROID polymerization by structurally activating TORC1

Target of rapamycin complex 1 (TORC1) is a protein kinase controlling cell homeostasis and growth in response to nutrients and stresses. In Saccharomyces cerevisiae, glucose depletion triggers a redistribution of TORC1 from a dispersed localization over the vacuole surface into a large, inactive con...

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Detalles Bibliográficos
Autores principales: Prouteau, Manoël, Bourgoint, Clélia, Felix, Jan, Bonadei, Lenny, Sadian, Yashar, Gabus, Caroline, Savvides, Savvas N., Gutsche, Irina, Desfosses, Ambroise, Loewith, Robbie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10023571/
https://www.ncbi.nlm.nih.gov/pubmed/36702972
http://dx.doi.org/10.1038/s41594-022-00912-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10023571/
https://www.ncbi.nlm.nih.gov/pubmed/36702972
http://dx.doi.org/10.1038/s41594-022-00912-6

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