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EGOC inhibits TOROID polymerization by structurally activating TORC1
Target of rapamycin complex 1 (TORC1) is a protein kinase controlling cell homeostasis and growth in response to nutrients and stresses. In Saccharomyces cerevisiae, glucose depletion triggers a redistribution of TORC1 from a dispersed localization over the vacuole surface into a large, inactive con...
Autores principales: | Prouteau, Manoël, Bourgoint, Clélia, Felix, Jan, Bonadei, Lenny, Sadian, Yashar, Gabus, Caroline, Savvides, Savvas N., Gutsche, Irina, Desfosses, Ambroise, Loewith, Robbie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10023571/ https://www.ncbi.nlm.nih.gov/pubmed/36702972 http://dx.doi.org/10.1038/s41594-022-00912-6 |
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