Data integration across conditions improves turnover number estimates and metabolic predictions

Turnover numbers characterize a key property of enzymes, and their usage in constraint-based metabolic modeling is expected to increase the prediction accuracy of diverse cellular phenotypes. In vivo turnover numbers can be obtained by integrating reaction rate and enzyme abundance measurements from...

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Detalles Bibliográficos
Autores principales: Wendering, Philipp, Arend, Marius, Razaghi-Moghadam, Zahra, Nikoloski, Zoran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10023748/
https://www.ncbi.nlm.nih.gov/pubmed/36932067
http://dx.doi.org/10.1038/s41467-023-37151-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10023748/
https://www.ncbi.nlm.nih.gov/pubmed/36932067
http://dx.doi.org/10.1038/s41467-023-37151-2

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