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The protective role of conjunctival goblet cell mucin sialylation

Gel-forming mucins secreted by conjunctival goblet cells have been implicated in the clearance of allergens, pathogens, and debris. However, their roles remain incompletely understood. Here we show that human and mouse conjunctival goblet cell mucins have Alcian blue-detectable sialic acids, but not...

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Detalles Bibliográficos
Autores principales: Matsuzawa, Moe, Ando, Tomoaki, Fukase, Saaya, Kimura, Meiko, Kume, Yasuharu, Ide, Takuma, Izawa, Kumi, Kaitani, Ayako, Hara, Mutsuko, Nakamura, Eri, Kamei, Anna, Matsuda, Akira, Nakano, Nobuhiro, Maeda, Keiko, Tada, Norihiro, Ogawa, Hideoki, Okumura, Ko, Murakami, Akira, Ebihara, Nobuyuki, Kitaura, Jiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10023771/
https://www.ncbi.nlm.nih.gov/pubmed/36932081
http://dx.doi.org/10.1038/s41467-023-37101-y