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Kinin B(1) and B(2) receptors mediate cancer pain associated with both the tumor and oncology therapy using aromatase inhibitors

Pain caused by the tumor or aromatase inhibitors (AIs) is a disabling symptom in breast cancer survivors. Their mechanisms are unclear, but pro-algesic and inflammatory mediators seem to be involved. Kinins are endogenous algogenic mediators associated with various painful conditions via B(1) and B(...

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Detalles Bibliográficos
Autores principales: Brusco, Indiara, Becker, Gabriela, Palma, Tais Vidal, Pillat, Micheli Mainardi, Scussel, Rahisa, Steiner, Bethina Trevisol, Sampaio, Tuane Bazanella, Ardisson-Araújo, Daniel Mendes Pereira, de Andrade, Cinthia Melazzo, Oliveira, Mauro Schneider, Machado-De-Avila, Ricardo Andrez, Oliveira, Sara Marchesan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10023805/
https://www.ncbi.nlm.nih.gov/pubmed/36932156
http://dx.doi.org/10.1038/s41598-023-31535-6