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Kinin B(1) and B(2) receptors mediate cancer pain associated with both the tumor and oncology therapy using aromatase inhibitors
Pain caused by the tumor or aromatase inhibitors (AIs) is a disabling symptom in breast cancer survivors. Their mechanisms are unclear, but pro-algesic and inflammatory mediators seem to be involved. Kinins are endogenous algogenic mediators associated with various painful conditions via B(1) and B(...
Autores principales: | Brusco, Indiara, Becker, Gabriela, Palma, Tais Vidal, Pillat, Micheli Mainardi, Scussel, Rahisa, Steiner, Bethina Trevisol, Sampaio, Tuane Bazanella, Ardisson-Araújo, Daniel Mendes Pereira, de Andrade, Cinthia Melazzo, Oliveira, Mauro Schneider, Machado-De-Avila, Ricardo Andrez, Oliveira, Sara Marchesan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10023805/ https://www.ncbi.nlm.nih.gov/pubmed/36932156 http://dx.doi.org/10.1038/s41598-023-31535-6 |
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