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Splicing signature database development to delineate cancer pathways using literature mining and transcriptome machine learning

Alternative splicing (AS) events modulate certain pathways and phenotypic plasticity in cancer. Although previous studies have computationally analyzed splicing events, it is still a challenge to uncover biological functions induced by reliable AS events from tremendous candidates. To provide essent...

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Detalles Bibliográficos
Autores principales: Lee, Kyubin, Hyung, Daejin, Cho, Soo Young, Yu, Namhee, Hong, Sewha, Kim, Jihyun, Kim, Sunshin, Han, Ji-Youn, Park, Charny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10023904/
https://www.ncbi.nlm.nih.gov/pubmed/36942103
http://dx.doi.org/10.1016/j.csbj.2023.02.052