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Saturated fatty acid– and/or monounsaturated fatty acid–containing phosphatidic acids selectively interact with heat shock protein 27

Diacylglycerol kinase (DGK) α, which is a key enzyme in the progression of cancer and, in contrast, in T-cell activity attenuation, preferentially produces saturated fatty acid (SFA)– and/or monounsaturated fatty acid (MUFA)–containing phosphatidic acids (PAs), such as 16:0/16:0-, 16:0/18:0-, and 16...

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Detalles Bibliográficos
Autores principales: Yachida, Naoto, Hoshino, Fumi, Murakami, Chiaki, Ebina, Masayuki, Miura, Yuri, Sakane, Fumio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10023972/
https://www.ncbi.nlm.nih.gov/pubmed/36791913
http://dx.doi.org/10.1016/j.jbc.2023.103019