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Combination of epigenetic erasing and mechanical cues to generate human epiBlastoids from adult dermal fibroblasts
PURPOSE: This study is to develop a new protocol that combines the use of epigenetic cues and mechanical stimuli to assemble 3D spherical structures, arbitrarily defined “epiBlastoids,” whose phenotype is remarkably similar to natural embryos. METHODS: A 3-step approach is used to generate epiBlasto...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024007/ https://www.ncbi.nlm.nih.gov/pubmed/36933093 http://dx.doi.org/10.1007/s10815-023-02773-4 |