Hepatitis C virus E1 and modified E2 delivered from an mRNA vaccine induces protective immunity

Hepatitis C virus (HCV) is characterized by a high number of chronic cases due to an impairment of protective innate and adaptive immune responses. Here, we examined the contribution of the individual ectodomains of E1, E2, or a modified E2 with reduced CD81 binding and an inserted N-linked glycosyl...

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Detalles Bibliográficos
Autores principales: Patra, Tapas, Meyer, Keith, Haga, Yuki, Reagan, Erin K., Weissman, Drew, Ray, Ranjit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024013/
https://www.ncbi.nlm.nih.gov/pubmed/36934116
http://dx.doi.org/10.1038/s41541-023-00635-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024013/
https://www.ncbi.nlm.nih.gov/pubmed/36934116
http://dx.doi.org/10.1038/s41541-023-00635-9

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