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Hepatitis C virus E1 and modified E2 delivered from an mRNA vaccine induces protective immunity
Hepatitis C virus (HCV) is characterized by a high number of chronic cases due to an impairment of protective innate and adaptive immune responses. Here, we examined the contribution of the individual ectodomains of E1, E2, or a modified E2 with reduced CD81 binding and an inserted N-linked glycosyl...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024013/ https://www.ncbi.nlm.nih.gov/pubmed/36934116 http://dx.doi.org/10.1038/s41541-023-00635-9 |