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Inflammatory stimuli induce shedding of heparan sulfate from arterial but not venous porcine endothelial cells leading to differential proinflammatory and procoagulant responses

Endothelial dysfunction is an early event of vascular injury defined by a proinflammatory and procoagulant endothelial cell (EC) phenotype. Although endothelial glycocalyx disruption is associated with vascular damage, how various inflammatory stimuli affect the glycocalyx and whether arterial and v...

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Detalles Bibliográficos
Autores principales: Milusev, Anastasia, Despont, Alain, Shaw, Jane, Rieben, Robert, Sorvillo, Nicoletta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024017/
https://www.ncbi.nlm.nih.gov/pubmed/36934164
http://dx.doi.org/10.1038/s41598-023-31396-z