Metabolic alterations precede neurofilament changes in presymptomatic ALS gene carriers

BACKGROUND: The emergence of potentially effective new therapies for genetic forms of amyotrophic lateral sclerosis (ALS) necessitates the identification of biomarkers to facilitate early treatment, prior to the onset of motor symptoms. Here, we sought to investigate whether metabolic alterations ar...

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Detalles Bibliográficos
Autores principales: Dorst, Johannes, Weydt, Patrick, Brenner, David, Witzel, Simon, Kandler, Katharina, Huss, André, Herrmann, Christine, Wiesenfarth, Maximilian, Knehr, Antje, Günther, Kornelia, Müller, Kathrin, Weishaupt, Jochen H., Prudlo, Johannes, Forsberg, Karin, Andersen, Peter M., Rosenbohm, Angela, Schuster, Joachim, Roselli, Francesco, Dupuis, Luc, Mayer, Benjamin, Tumani, Hayrettin, Kassubek, Jan, Ludolph, Albert C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024076/
https://www.ncbi.nlm.nih.gov/pubmed/36917918
http://dx.doi.org/10.1016/j.ebiom.2023.104521

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024076/
https://www.ncbi.nlm.nih.gov/pubmed/36917918
http://dx.doi.org/10.1016/j.ebiom.2023.104521

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