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Implantation of engineered human microvasculature to study human infectious diseases in mouse models

Animal models for studying human pathogens are crucially lacking. We describe the implantation in mice of engineered human mature microvasculature consisting of endothelial and perivascular cells embedded in collagen hydrogel that allows investigation of pathogen interactions with the endothelium, i...

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Detalles Bibliográficos
Autores principales: Schönherr-Hellec, Sophia, Chatzopoulou, Eirini, Barnier, Jean-Philippe, Atlas, Yoann, Dupichaud, Sébastien, Guilbert, Thomas, Dupraz, Yves, Meyer, Julie, Chaussain, Catherine, Gorin, Caroline, Nassif, Xavier, Germain, Stephane, Muller, Laurent, Coureuil, Mathieu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024136/
https://www.ncbi.nlm.nih.gov/pubmed/36942053
http://dx.doi.org/10.1016/j.isci.2023.106286