Integration of ATAC-Seq and RNA-Seq identifies key genes and pathways involved in the neuroprotection of S-adenosylmethionine against perioperative neurocognitive disorder

The gene-regulatory landscape is highly dynamic in healthy and diseased brains. DNA methylation is a well-known epigenetic modification that regulates gene expression, and our previous study demonstrated that S-adenosylmethionine (SAM), a methylome modulator, was a neuroprotectant against perioperat...

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Detalles Bibliográficos
Autores principales: Xu, Feifei, Cong, Peilin, Lu, Zhihong, Shi, Liwen, Xiong, Lize, Zhao, Guanghou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024148/
https://www.ncbi.nlm.nih.gov/pubmed/36942104
http://dx.doi.org/10.1016/j.csbj.2023.03.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024148/
https://www.ncbi.nlm.nih.gov/pubmed/36942104
http://dx.doi.org/10.1016/j.csbj.2023.03.001

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