Metformin and simvastatin exert additive antitumour effects in glioblastoma via senescence-state: clinical and translational evidence

BACKGROUND: Glioblastoma is one of the most devastating and incurable cancers due to its aggressive behaviour and lack of available therapies, being its overall-survival from diagnosis ∼14-months. Thus, identification of new therapeutic tools is urgently needed. Interestingly, metabolism-related dru...

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Detalles Bibliográficos
Autores principales: Fuentes-Fayos, Antonio C., G-García, Miguel E., Pérez-Gómez, Jesús M., Montero-Hidalgo, Antonio J., Martín-Colom, Julia, Doval-Rosa, Carlos, Blanco-Acevedo, Cristóbal, Torres, Encarnación, Toledano-Delgado, Álvaro, Sánchez-Sánchez, Rafael, Peralbo-Santaella, Esther, Ortega-Salas, Rosa M., Jiménez-Vacas, Juan M., Tena-Sempere, Manuel, López, Miguel, Castaño, Justo P., Gahete, Manuel D., Solivera, Juan, Luque, Raúl M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024193/
https://www.ncbi.nlm.nih.gov/pubmed/36907105
http://dx.doi.org/10.1016/j.ebiom.2023.104484

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024193/
https://www.ncbi.nlm.nih.gov/pubmed/36907105
http://dx.doi.org/10.1016/j.ebiom.2023.104484

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